Articles Tagged With:
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PATH-s Tool Helps Caregivers Understand What Is Needed
Researchers developed a transition care tool that helps caregivers better understand their role and what is expected of them in supporting and caring for patients. A new study on the Preparedness Assessment for the Transition Home After Stroke revealed what caregivers understand about patients’ disease and their own role.
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Take Steps to Prevent Damaging Security Breaches in Survey Studies
IRBs can help investigators create a plan to prevent survey security breaches that can lead to false data and study slowdowns and shutdowns. IRBs should ensure researchers know that if they detect a breach that changes/corrupts data, leads to someone outside the research team accessing data, causes potential harm to participants, or requires a change in procedures or informed consent, it should be reported to the IRB.
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IRBs, Researchers Starting to Recognize Security Breaches of Online Survey Data
Researchers at the University of Houston discovered a survey study had been breached. Large number of surveys poured in, with batches arriving in two-minute intervals. Other signs of a breach included suspicious responses, unusual email addresses and patterns, responses from outside the United States, and missing contact information.
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United Kingdom Begins First COVID-19 Human Challenge Study
Lawmakers, academics, and the research community have hotly debated the ethics of a human challenge study since the first months of the COVID-19 pandemic. Now that the United Kingdom has started dosing patients in its human challenge study, some bioethicists say this trial can show vaccine efficacy in ways the larger vaccine trials cannot.
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Study of COVID-19 Vaccine in Pregnant People ‘Too Late’
On Feb. 18, Pfizer and BioNTech announced they would dose about 4,000 healthy pregnant women with the COVID-19 vaccine to evaluate its safety, tolerability, and immunogenicity. Although pregnant people were excluded initially from the COVD-19 trials, research has shown they are at higher risk for more severe disease.
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Employing Technology and Exergames to Improve Balance Post-Stroke
This small pilot study reveals potential for exergames (activity-based video games) to be used as a telemedicine rehabilitation intervention in improving balance and function in patients six to eight weeks post-stroke.
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Dairy, Bone Health, and Menopause
An analysis of data from the Study of Women’s Health Across the Nation cohort did not reveal a significant association between daily dairy intake frequency, femoral and spine bone mineral density loss, and non-traumatic fracture risk among women transitioning to menopause.
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Exercise Intervention for Improving Metabolic Associated Fatty Liver
A small interventional study assessed the histological appearance of liver biopsies from patients with metabolic associated fatty liver disease (MAFLD) who completed 12-weeks of structured and supported aerobic exercise. Compared to biopsies from a nonexercising control group, the intervention arm demonstrated some reversal of histopathologic changes caused by MAFLD.
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Atorvastatin and Low-Dose Dexamethasone for Treatment of Chronic Subdural Hematoma
Chronic subdural hematoma is a common cause of serious neurological morbidity and mortality in the elderly population. Atorvastatin has both an anti-inflammatory effect and the ability to mobilize endothelial progenitor cells, which assist in vascular repair. The investigators proposed that adding a low dose of dexamethasone to atorvastatin treatment might enhance the anti-inflammatory benefits without causing the side effects associated with high doses of corticosteroids.
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Tranexamic Acid in Patients with Intracerebral Hemorrhage Does Not Improve Outcomes
Primary intracerebral hemorrhage is a major cause of severe neurological disability and carries a high rate of death. Tranexamic acid was tested in a study of 2,325 patients with intracerebral hemorrhage within eight hours of symptom onset, but did not significantly improve neurological outcome.